Rio Marthin1 | Dwi Hari Susilo2 | Maryono Dwi Wibowo3
Thyroid cancer is one of the most frequent cases in a thyroid nodule and vitamin D levels are found very influential on the condition of malignancy and the low levels of vitamin D indicate the condition of the disease is bad. TSH levels are associated with an increase in the risk of Thyroid cancer. The study is examining the relationship vitamin D and TSH with of thyroid cancer. The type of this research was analytic observational in a cross-sectional design. Samples were 30 patient tyroid cancer by taking the data levels of vitamin D that were taken from the examination of the blood of patients 1 day before the patients taking the operation. TSH levels were taken from the history of the examination of patients in the outpatient clinic. In this study, it was found that TSH levels at the study ‘s average was 1.4051 mIU/L. Vitamin D level had average levels of 24.5 ng/mL. After examination, we found that 7 research subjects were benign thyroid tumors (23.3%), and 23 subjects were identified as malignant thyroid tumors (76.7%). TSH levels do not have a relationship that is significant with p value = 0.323. While the levels of vitamin D have a significant relationship in statistics with the malignancy of thyroid which is evidenced by p value of 0.003. The relationships are significant in statistics between levels of vitamin D against malignancy in patients with nodules of the thyroid and no significant relationship in statistics between the levels of thyroid-stimulating hormone to malignancy in patients with a thyroid nodule.
Keywords: Nodular Thyroid Carcinoma, vitamin D level, Thyroid Stimulating Hormone