Analysis of the Correlation between the Level of Adherence on Anti-Hypertensive Drugs Usage and JNC (Joint National Committee) VIII Blood Pressure Targets

Rizal

Abstract: Adherence in doing a therapy for hypertensive patients is an important thing to note seeing that hypertension is a disease which cannot be cured but can only be controlled. The success of controlling blood pressure for hypertensive patients is influenced by adherence factor in taking anti-hypertensive drugs. This research aims to analyze correlation between the level of adherence on anti-hypertensive drugs usage and JNC VIII blood pressure targets. The research design used was observational cross sectional which the subjects are hypertensive patients who are older than or equal to 18 years old in the outpatient’s installation of Robert Wolter Monginsidi Manado Hospital and Kotabunan Bolaang Mongondow Health Centre in the period of October to December 2019. Level of adherence on Anti-Hypertensive drugs usage was assessed by MMAS-8 questionnaire (Morisky 8-Item Medication Adherence Scale). Total patients in this research are 175 in which 83.43% are classified having low adherence level (MMAS score <6) and 16.57% classified having moderate to high adherence level (MMAS score 6-8). Furthermore, 9.71% of blood pressure target based on JNC VIII is on target and 90.29% is not on target (blood pressure uncontrolled). Based on the respondent characteristic, level of education, length of treatment had significant relation (p < 0.05) over the patients’ adherence level in taking anti-hypertensive drugs and JNC VIII blood pressure targets. The correlation between adherence level based on MMAS scale (146 patients are classified in the low level, 22 patients are classified in the moderate level, and 7 patients are classified in the high level) with JNC blood pressure targets (17 patients are on target and 158 are not on target) showed the significant correlation with p value: 0.000 and correlative coefficient is 0.772 (strong correlation). Based on the result above, it is suggested that each hospital and health center requires its pharmacists to do pharmaceutical practices, and each pharmacy must not provide medication services without the presence of pharmacist.

Keywords:   Hypertension, Adherence, JNC

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