Management of Therapy in Hepatic Cirrhosis

 ^Authors: Herni Setyawati¹, Yulistiani^2,3

¹Magister Farmasi Klinik, Fakultas Farmasi Universitas Airlangga, Surabaya, Indonesia,

²Departemen Farmasi Klinik, Fakultas Farmasi Universitas Airlangga, Surabaya, Indonesia,

³Divisi Farmasi Klinik Rumah Sakit Universitas Airlangga, Surabaya, Indonesia

Email: hernisetyawati285@gmail.com

Abstract

The liver is the largest organ of the human body with many important functions. The presence of histopotologis conditions, such as the formation of fibrosis in the liver will affect liver function. Hepatic cirrhosis is characterized by diffuse fibrous formation and nodular formation, accompanied by various clinical manifestations and complications.Sirosis is the 12th leading cause of death in the United States which accounted for 29,165 deaths in 2007, with mortality of 9.7 per 100,000 people. Various pharmacological treatments in hepatic cirrhosis are used to treat underlying causes, preserve nutrients and overcome the emerging complications, including portal hypertension, variceal haemorrhage, splenomegaly, ascites, spontaneous bacterial peritonitis (SBP), hepatorenal syndrome and hepatic encephalopathy. This review aims to describe the pharmaceutical aspects of pharmacological therapy used in the management of hepatic cirrhosis.

Keywords:  hepatic cirrhosis, management theraphy

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