Glutamine as an Alternative Nutrition in Clinical Practices

^Authors: Ana Nurlaili Hidayah¹, Nurul Ma’rifah², Widyanti Afifah³, Didik Hasmono⁴

¹Master Program of Clinical Pharmacy, ³Master Program of Clinical Pharmacy,

⁴Faculty of Pharmacy, Airlangga University

Abstract

Glutamine appears as an essential amino acid in patients with catabolic disease. Glutamine is the most abundant amino acid in the blood and free amino acid pool in the body that has a five-carbon Glutamine supplementation has been associated with reduced mortality, infections and hospital length of stay in critically ill patients and patients undergoing major surgery. Parenteral nutrition (PN) glutamine supplementation may be advantageous in certain other adult surgical patients or critically ill non-ventilated patients requiring PN. A positive impact of PN glutamine supplementation in hematopoietic stem cell transplant recipients, burn patients, and patients with severe acute pancreatitis remains unclear and warrants large, well designed, randomized control trial

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