Pharmacologic Therapy in Peripheral Artery Disease

^Authors: Lelly Winduhani A¹, Dea Ayu Nabilah¹, Suharjono²

¹Master of Clinical Pharmacy, ²Department Of Clinical Pharmacy,

Faculty of Pharmacy, Airlangga University, Surabaya, Indonesia

Email: shj_ms_id@yahoo.co.id & lelly.hani@gmail.com

Abstract

Peripheral artery disease (PAD) is a common and disabling health condition affecting 20% over age 75. This disease happen in extremities, carotid artery, renalis artery, mesentrica artery.  PAD could be happen because of structure or function change in vessel. Peripheral artery disease commonly caused by atherosclerotic plaque in the arteries. The most common manifestation is intermittent claudication. Complication of PAD such as critical limb ischemia, skin ulceration, gangrene, and amputation. Pharmacologic therapy is important for patient with PAD such as antihyperlipidemia and antiplatelet. Antihyperlipidemia is one most important medication for PAD. Not only pharmacologic therapy is needed but also therapeutic lifestyle changes to modify cardiovascular disease such as stop smoking, hypertension, diabetes. Optimize medication is needed to decrease morbidity an increase quality of life.

Keyword: Peripheral Artery Disease, Antihyperlipidemia, Antiplatelet

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