Corn Oil can Lower Levels of Total Cholesterol and MDA (Malondialdehid) in The White Rat (Rattus norvegicus)

^{Authors: 1}Ayu Lestari, ²Bambang Wijatmadi, ³Merryana Adriani, ⁴Rr. Soenarnatalina M., ⁵Dwi Winarni, ⁶Sri Hartiningsih

¹Master Student at at Faculty of Public Health, Airlangga University. Indonesia

 ^2,3,4Lecturer at Faculty of Public Health, Airlangga University. Indonesia

 ⁵Lecturer at Faculty of Science and Technology, Airlangga University, Indonesia

⁶Lecturer at Faculty of Medicine, Hang Tuah University, Indonesia

 Abstract

Repeatedly–heated cooking oil produces trans fatty acids and high free fatty acids that can increase total cholesterol levels. Used cooking oil also contains free radical compounds that can attack the lipid component through the mechanism of cell membrane lipid destruction. Efforts that can be made to minimize the negative impact of using used cooking oil is to replace it with healthy oil. Corn oil is a vegetable oil containing unsaturated fatty acids, high vitamin E, and phytosterols that are very beneficial for body. This study aimed to prove corn oil effect on total cholesterol reduction and malondialdehid levels in wistar rats Rattus norvegicus) treated with used cooking oil. This research was an experimental research with post test control group design. This study used 25 male wistar rats as a sample that divided into 5 groups, namely: (1) negative control group (with standard diet); (2) positive control group (given 0.5 mL used cooking oil); (3) treatment group 1 (given 0.5 mL/day of cooking oil + corn oil 0.321 mL/day); (4) treatment group 2 (given 0 fried oil 0.5 mL/day + corn oil 0.641 mL/day); and (5) treatment group 3 (given 0.5 mL/day of cooking oil + corn oil 0.962 mL/day). The results showed that there was a decrease of mean total cholesterol level in treatment group with significant difference (p < 0.05). Mean malondialdehyde levels in the treatment group also decreased with a significant difference (p < 0.05). Corn oil treatment could reduce total cholesterol and malondialdehid levels in wistar rats that were given significant used cooking oil.

Keywords: Corn oil, Total cholesterol, Malondialdehyde

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