Pharmacologic Therapy of Familial Hypercholesterolemia in Cardiovascular Disease

^Authors: Khoirunnisa¹, Gretta Niken Purbosari¹, Suharjono²

¹Master of Clinical Pharmacy, ²Department Of Clinical Pharmacy,

Faculty of Pharmacy, Airlangga University, Surabaya, Indonesia

Abstract

Cardiovascular disease is a major health problem in almost all countries of the world and contributes to about 30 percent of all deaths in the world. Cardiovascular disease is a group of diseases caused by disorders of the heart or blood vessels. Some of the diseases included in this group include coronary heart disease, cerebrovascular disease (stroke), hypertension, peripheral vascular disease, valve disease, congenital heart disease, and heart failure. The major risk factors for cardiovascular disease that are known to date include age, sex, diabetes mellitus, dyslipidemia, smoking, physical inactivation, improper diet and alcohol consumption. Strategies for the treatment and prevention of cardiovascular disease can be highly effective and have been subjected to rigorous evaluation. The evidence base for the treatment of cardiovascular disease is stronger than for almost any other disease group.

Keyword: cardiovascular disease, atherosclerosis, hypercholesterolemia, antihyperlipidemia

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