Authors: Ananda Mellyani Hidayat1, Yulistiani2
1Master of Clinical Pharmacy, 2Department of Clinical Pharmacy,
Faculty of Pharmacy, Airlangga University, Surabaya, Indonesia
Email: yulist_r@yahoo.co.id | anandamellyani@gmail.com
Abstract
Chronic Kidney Disease (CKD) refers to a condition with an irreversible kidney damage that can progress to end-stage renal disease. CKD in childhood presents clinical features that are specific and give an impact to the pediatric age. . The prevalence of CKD is about 1.5 to 3.0 per 1,000,000 among children younger than the age of 16 years per year. The main etiologic factors of CKD in children are caused by congenital abnormalities of the kidney and urinary tract, steroid-resistant nephrotic syndrome, chronic glomerulonephritis and renal ciliopathies. Chronic Kidney Disease is a disease that affects multiple systems, including calcium-phosphorus metabolism, growth, hematologic and cardiovascular systems. The general management of children with CKD includes treating reversible kidney dysfunction, preventing the progression of CKD and treating the complications associated with CKD.
Keywords: Chronic Renal Failure, CKD, pediatrics, management