Authors: Fitri Amalia1, Annis Catur Adi2, Windhu Purnomo3
1Master Student at Faculty of Public Health, Airlangga University, Indonesia
2Lecturer at Department of Nutrition, Faculty of Public Health, Airlangga University, Indonesia
3Lecturer at Department of Biosatistics and Population, Faculty of Public Health, Airlangga University, Indonesia
Abstract
Folate deficiency induces homocysteine efflux into the circulation by inhibiting remethylation pathway. That matter cause increasing circulating homocysteine levels, which commonly called hyperhomocysteinemia. Hyperhomocysteinemia is fully recognised as an independent risk factor for cardiovascular disease. This cross-sectional study examined association between serum folate and blood pressure on fisherman in Bulak District. An observational analytic with cross sectional design on 95 fishermen aged 26-≤60 years. After adjusted with inclusion and exclusion criteria then 31 fishermen participated in this study. The sample frame on this study is the list of fishermen names who still on duty, owned by the fisherman chief. Binary logistic regression test showed no correlation between serum folate level with prehypertension and hypertension by means of significance value p = 0,573. The incidence of hypertension and prehypertension occured in fishermen aged ≥40 years, in poor fishermen with limited education. Serum folate of respondent was normal (>3ng/mL) but folate intake of respondents inadequate compared to Recommended Dietary Allowance (RDA). We conclude that there is no association between serum folate with high blood pressure. Respondent’s folate serum was normal despite low of folate intake because supporting nutritional intake of vitamins B12 and B6 were adequate.
Keywords: Blood pressure, folate, homocystein, dietary intake, nutrition
